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math1 .11d  (Genvec Inc)

 
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    Genvec Inc math1 .11d
    Efficient HC ablation after DT injection and adenovirus scala media inoculation. Images show cochleae of adult mice 10 days after adenoviral inoculation of scala media with or without HC ablation. ( a , a ′, b , b ′) Ad. Atoh1 adenovirus inoculation of wild-type (WT) mouse without DT-induced HC ablation. ( c , c ′, d , d ′) Ad. Atoh1 adenovirus inoculation of Pou4F3 DTR mouse with simultaneous DT injection. ( e , e ′, f , f ′) adenovirus Ad. Gfi1.Atoh1 inoculation of Pou4F3 DTR mouse with simultaneous DT injection. Dotted lines in a, b indicate where OHCs would be found in normal mice. In animals receiving only the injection surgery, most outer HCs are damaged and only a few OHCs remain in the most apical region, but inner HCs are largely intact. In contrast, all HCs both outer HCs and inner HCs, are ablated by simultaneous DT injection in both the Ad. Atoh1 group ( c , d ) and the Ad. Gfi1.Atoh1 group ( e , f ). All groups robustly expressed the tdTomato reporter ( a ′– f ′). Myosin VIIa, Myosin VIIa. tdTom, tdTomato. Representative figures from 5 biological replicates for each group. Scale bar = 100 μm.
    Math1 .11d, supplied by Genvec Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/math1 .11d/product/Genvec Inc
    Average 90 stars, based on 1 article reviews
    math1 .11d - by Bioz Stars, 2026-04
    90/100 stars

    Images

    1) Product Images from "Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea"

    Article Title: Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea

    Journal: Scientific Reports

    doi: 10.1038/s41598-020-78167-8

    Efficient HC ablation after DT injection and adenovirus scala media inoculation. Images show cochleae of adult mice 10 days after adenoviral inoculation of scala media with or without HC ablation. ( a , a ′, b , b ′) Ad. Atoh1 adenovirus inoculation of wild-type (WT) mouse without DT-induced HC ablation. ( c , c ′, d , d ′) Ad. Atoh1 adenovirus inoculation of Pou4F3 DTR mouse with simultaneous DT injection. ( e , e ′, f , f ′) adenovirus Ad. Gfi1.Atoh1 inoculation of Pou4F3 DTR mouse with simultaneous DT injection. Dotted lines in a, b indicate where OHCs would be found in normal mice. In animals receiving only the injection surgery, most outer HCs are damaged and only a few OHCs remain in the most apical region, but inner HCs are largely intact. In contrast, all HCs both outer HCs and inner HCs, are ablated by simultaneous DT injection in both the Ad. Atoh1 group ( c , d ) and the Ad. Gfi1.Atoh1 group ( e , f ). All groups robustly expressed the tdTomato reporter ( a ′– f ′). Myosin VIIa, Myosin VIIa. tdTom, tdTomato. Representative figures from 5 biological replicates for each group. Scale bar = 100 μm.
    Figure Legend Snippet: Efficient HC ablation after DT injection and adenovirus scala media inoculation. Images show cochleae of adult mice 10 days after adenoviral inoculation of scala media with or without HC ablation. ( a , a ′, b , b ′) Ad. Atoh1 adenovirus inoculation of wild-type (WT) mouse without DT-induced HC ablation. ( c , c ′, d , d ′) Ad. Atoh1 adenovirus inoculation of Pou4F3 DTR mouse with simultaneous DT injection. ( e , e ′, f , f ′) adenovirus Ad. Gfi1.Atoh1 inoculation of Pou4F3 DTR mouse with simultaneous DT injection. Dotted lines in a, b indicate where OHCs would be found in normal mice. In animals receiving only the injection surgery, most outer HCs are damaged and only a few OHCs remain in the most apical region, but inner HCs are largely intact. In contrast, all HCs both outer HCs and inner HCs, are ablated by simultaneous DT injection in both the Ad. Atoh1 group ( c , d ) and the Ad. Gfi1.Atoh1 group ( e , f ). All groups robustly expressed the tdTomato reporter ( a ′– f ′). Myosin VIIa, Myosin VIIa. tdTom, tdTomato. Representative figures from 5 biological replicates for each group. Scale bar = 100 μm.

    Techniques Used: Injection



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    math1 .11d  (Genvec Inc)
    90
    Genvec Inc math1 .11d
    Efficient HC ablation after DT injection and adenovirus scala media inoculation. Images show cochleae of adult mice 10 days after adenoviral inoculation of scala media with or without HC ablation. ( a , a ′, b , b ′) Ad. Atoh1 adenovirus inoculation of wild-type (WT) mouse without DT-induced HC ablation. ( c , c ′, d , d ′) Ad. Atoh1 adenovirus inoculation of Pou4F3 DTR mouse with simultaneous DT injection. ( e , e ′, f , f ′) adenovirus Ad. Gfi1.Atoh1 inoculation of Pou4F3 DTR mouse with simultaneous DT injection. Dotted lines in a, b indicate where OHCs would be found in normal mice. In animals receiving only the injection surgery, most outer HCs are damaged and only a few OHCs remain in the most apical region, but inner HCs are largely intact. In contrast, all HCs both outer HCs and inner HCs, are ablated by simultaneous DT injection in both the Ad. Atoh1 group ( c , d ) and the Ad. Gfi1.Atoh1 group ( e , f ). All groups robustly expressed the tdTomato reporter ( a ′– f ′). Myosin VIIa, Myosin VIIa. tdTom, tdTomato. Representative figures from 5 biological replicates for each group. Scale bar = 100 μm.
    Math1 .11d, supplied by Genvec Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/math1 .11d/product/Genvec Inc
    Average 90 stars, based on 1 article reviews
    math1 .11d - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Efficient HC ablation after DT injection and adenovirus scala media inoculation. Images show cochleae of adult mice 10 days after adenoviral inoculation of scala media with or without HC ablation. ( a , a ′, b , b ′) Ad. Atoh1 adenovirus inoculation of wild-type (WT) mouse without DT-induced HC ablation. ( c , c ′, d , d ′) Ad. Atoh1 adenovirus inoculation of Pou4F3 DTR mouse with simultaneous DT injection. ( e , e ′, f , f ′) adenovirus Ad. Gfi1.Atoh1 inoculation of Pou4F3 DTR mouse with simultaneous DT injection. Dotted lines in a, b indicate where OHCs would be found in normal mice. In animals receiving only the injection surgery, most outer HCs are damaged and only a few OHCs remain in the most apical region, but inner HCs are largely intact. In contrast, all HCs both outer HCs and inner HCs, are ablated by simultaneous DT injection in both the Ad. Atoh1 group ( c , d ) and the Ad. Gfi1.Atoh1 group ( e , f ). All groups robustly expressed the tdTomato reporter ( a ′– f ′). Myosin VIIa, Myosin VIIa. tdTom, tdTomato. Representative figures from 5 biological replicates for each group. Scale bar = 100 μm.

    Journal: Scientific Reports

    Article Title: Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea

    doi: 10.1038/s41598-020-78167-8

    Figure Lengend Snippet: Efficient HC ablation after DT injection and adenovirus scala media inoculation. Images show cochleae of adult mice 10 days after adenoviral inoculation of scala media with or without HC ablation. ( a , a ′, b , b ′) Ad. Atoh1 adenovirus inoculation of wild-type (WT) mouse without DT-induced HC ablation. ( c , c ′, d , d ′) Ad. Atoh1 adenovirus inoculation of Pou4F3 DTR mouse with simultaneous DT injection. ( e , e ′, f , f ′) adenovirus Ad. Gfi1.Atoh1 inoculation of Pou4F3 DTR mouse with simultaneous DT injection. Dotted lines in a, b indicate where OHCs would be found in normal mice. In animals receiving only the injection surgery, most outer HCs are damaged and only a few OHCs remain in the most apical region, but inner HCs are largely intact. In contrast, all HCs both outer HCs and inner HCs, are ablated by simultaneous DT injection in both the Ad. Atoh1 group ( c , d ) and the Ad. Gfi1.Atoh1 group ( e , f ). All groups robustly expressed the tdTomato reporter ( a ′– f ′). Myosin VIIa, Myosin VIIa. tdTom, tdTomato. Representative figures from 5 biological replicates for each group. Scale bar = 100 μm.

    Article Snippet: Math1 .11D (GenVec, Inc., Gaithersburg, MD, USA), used at a final concentration of 4 × 10 9 PU/ml.

    Techniques: Injection